Interpretation of new food raw materials for immune efficacy | Broccoli Seed Extract

- Jun 04, 2020-

As we all know, broccoli seed extracts have good performance in anti-cancer, promote detoxification and long-term antioxidant. Do you know its effect on immunity? Broccoli seed extract contains sulforaphane, which is absorbed by the body and reacts with myrosinase to produce sulforaphane. Sulforaphane not only has a strong anti-cancer activity but also has a strong antioxidant capacity. It is currently recognized as one of the natural products with anti-cancer, anti-cancer, and cosmetic effects. Sulforaphane is the most effective activator of the body's own immune system (Nrf2) pathway contained in food and has a wide range of protective effects.


Immune effect of broccoli seed extract

Enhancing the defense response of the antiviral host through nutritional supplements is an effective means of combating influenza. Studies have shown that after receiving live attenuated influenza virus (LAIV) vaccine in smokers, short-term intake of broccoli bud homogenate can reduce the marker of virus replication in nasal lavage fluid cells because broccoli bud homogenate The pulp contains a high concentration of sulforaphane precursor, which is the most effective pathway activator of the body's own immune system (Nrf2) contained in food and has a wide range of protection.

Ingesting broccoli bud homogenate in the body or supplementing it with epithelial cells can enhance the defense response of the antiviral host. In addition to affecting respiratory epithelial cells, it can also affect immune cells, including enhancing the clearance of bacteria by alveolar macrophages, enhancing the lytic activity of natural killer (NK) cells, and increasing natural killer (NK) in mouse models. )'S overall activity [1].

In 2015, a study showed that high and low doses of sulforaphane can significantly increase the decreased thymus index and spleen index of cyclophosphamide (Cy), suggesting that sulforaphane has certain protection and protection against Cy-suppressed immune organs. Promote the return to normal.

In the experiment, peritoneal macrophage phagocytosis was used as the non-specific immune function index, hemolysin test was used as the specific humoral immune index, and lymphocyte transformation was used as the cellular immune index. The regulatory effect. The results suggest that high and low doses of sulforaphane can increase the phagocytic percentage and phagocytic index of peritoneal macrophages, and promote the formation of hemolysin. A high dose of sulforaphane can significantly stimulate the transformation of lymphocytes. The high-dose sulforaphane's immune excitatory effect is strong, and the low-dose group is relatively weak. It is believed that sulforaphane's immunoprotective effect is positively correlated with the dose size. As the dose increases, the immune excitatory effect will be enhanced.

Research data shows that sulforaphane has the highest content in broccoli seeds. As the seeds germinate to grow, the content of sulforaphane will decrease.

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